Diagnosis Lab - Paphos Lab

Bordetella pertussis IgA

B. pertussis has the ability to inhibit the function of the host's immune system. The toxin, known as pertussis toxin (or PTx), inhibits G protein coupling that regulates an adenylate cyclase-mediated conversion of ATP to cyclic AMP. The end result is phagocytes convert too much ATP to cyclic AMP, which can cause disturbances in cellular signaling mechanisms, and prevent phagocytes from correctly responding to an infection. PTx, formerly known as lymphocytosis-promoting factor, causes a decrease in the entry of lymphocytes into lymph nodes, which can lead to a condition known as lymphocytosis, with a complete lymphocyte count of over 4000/μl in adults or over 8000/μl in children.

 

Specimen: 0.2 ml Serum

Reference Values:

<8 IU/ml  Negative
8-11 IU/ml  Probably   recent  infection
>11 IU/ml  Recent infection           

Method: ELISA

Loinc: 29672-3

Analysis Index

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Working hours

Main branch:
Andrea Vlami & Andrea Ellina corner, (opposite Paphos Home Market), 8025, Paphos, Cyprus
Working hours: Monday - Friday 7-7, Saturday Closed

Blood Sampling Site:
Vasileos Constantinou 36, 8021 Paphos, Cyprus
Working hours: Monday - Friday 7-5, Saturday Closed

Contact us

Tel: (+357) 26 815 900

Fax: (+357) 26 923 222

Email: info@diagnosislabcenter.com